Version 5.4
Bos taurus Protein: IL12RB2
Summary
InnateDB Protein IDBP-690159.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol IL12RB2
Protein Name interleukin-12 receptor subunit beta-2 precursor
Synonyms IL-12RB2;
Species Bos taurus
Ensembl Protein ENSBTAP00000012441
InnateDB Gene IDBG-638111 (IL12RB2)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 8 interaction(s) predicted by orthology.
Predicted by orthology
Total 8 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004896 cytokine receptor activity
GO:0005515 protein binding
GO:0019901 protein kinase binding
Biological Process
GO:0018108 peptidyl-tyrosine phosphorylation
GO:0019221 cytokine-mediated signaling pathway
GO:0032496 response to lipopolysaccharide
GO:0032609 interferon-gamma production
GO:0032729 positive regulation of interferon-gamma production
GO:0034097 response to cytokine
Cellular Component
GO:0009897 external side of plasma membrane
GO:0016020 membrane
Protein Structure and Domains
PDB ID
InterPro IPR003961 Fibronectin, type III
IPR010457 Immunoglobulin C2-set-like, ligand-binding
IPR015321 Interleukin-6 receptor alpha, binding
PFAM PF00041
PF01108
PF06328
PF09240
PRINTS
PIRSF
SMART SM00060
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL F1MEB5
UniProt Splice Variant
Entrez Gene 282452
UniGene Bt.7213
RefSeq NP_777070
HUGO HGNC:5972
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02008477 DAAA02008478
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca