InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: EN2

Summary

InnateDB Protein

IDBP-690268.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

EN2

Protein Name

engrailed homeobox 2

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000028648

InnateDB Gene

IDBG-638217 (EN2)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.

Predicted by orthology
Total	2 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000976	transcription regulatory region sequence-specific DNA binding
GO:0003677	DNA binding
GO:0003700	sequence-specific DNA binding transcription factor activity
GO:0043565	sequence-specific DNA binding

Biological Process

GO:0006355	regulation of transcription, DNA-templated
GO:0007275	multicellular organismal development
GO:0030182	neuron differentiation
GO:0030901	midbrain development
GO:0030902	hindbrain development
GO:0045944	positive regulation of transcription from RNA polymerase II promoter
GO:0048666	neuron development

Cellular Component

GO:0005634

nucleus

Protein Structure and Domains

PDB ID

InterPro

IPR000047 Helix-turn-helix motif
IPR000747 Homeodomain engrailed
IPR001356 Homeobox domain
IPR009057 Homeodomain-like
IPR020479 Homeodomain, metazoa

PFAM

PF00046

PRINTS

PR00031
PR00026
PR00024

PIRSF

SMART

SM00389

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

F1MXQ1

UniProt Splice Variant

Entrez Gene

UniGene

RefSeq

HUGO

HGNC:3343

OMIM

CCDS

HPRD

IMGT

EMBL

DAAA02012122 DAAA02012123

GenPept