Version 5.4
Bos taurus Protein: NIPA2
Summary
InnateDB Protein IDBP-690920.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol NIPA2
Protein Name Magnesium transporter NIPA2
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000022471
InnateDB Gene IDBG-638820 (NIPA2)
Protein Structure
UniProt Annotation
Function Acts as a selective Mg(2+) transporter. {ECO:0000250}.
Subcellular Localization Cell membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}. Early endosome {ECO:0000250}. Note=Recruited to the cell membrane in response to low extracellular magnesium. {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0015095 magnesium ion transmembrane transporter activity
Biological Process
GO:0006810 transport
GO:0006811 ion transport
GO:0015693 magnesium ion transport
Cellular Component
GO:0005768 endosome
GO:0005769 early endosome
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID
InterPro IPR000620 Drug/metabolite transporter
IPR008521 Magnesium transporter NIPA
PFAM PF00892
PF05653
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q3SWX0
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 507430
UniGene Bt.37647
RefSeq NP_001029470
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC104627
GenPept AAI04628

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca