InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: PNPO

Summary

InnateDB Protein

IDBP-691112.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

PNPO

Protein Name

Pyridoxine-5'-phosphate oxidase

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000016263

InnateDB Gene

IDBG-638999 (PNPO)

Protein Structure

UniProt Annotation

Function

Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP). {ECO:0000250}.

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.

Predicted by orthology
Total	3 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004733	pyridoxamine-phosphate oxidase activity
GO:0010181	FMN binding
GO:0016491	oxidoreductase activity
GO:0016638	oxidoreductase activity, acting on the CH-NH2 group of donors

Biological Process

GO:0008615	pyridoxine biosynthetic process
GO:0042823	pyridoxal phosphate biosynthetic process
GO:0055114	oxidation-reduction process

Cellular Component

GO:0070062

extracellular vesicular exosome

Protein Structure and Domains

PDB ID

InterPro

IPR000659 Pyridoxamine 5\'-phosphate oxidase
IPR011576 Pyridoxamine 5\'-phosphate oxidase-like, FMN-binding domain
IPR012349 FMN-binding split barrel
IPR019576 Pyridoxine 5\'-phosphate oxidase, dimerisation, C-terminal

PFAM

PF01243
PF10590

PRINTS

PIRSF

PIRSF000190

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q5E9K3