Version 5.4
Bos taurus Protein: PSMG1
Summary
InnateDB Protein IDBP-691265.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PSMG1
Protein Name Proteasome assembly chaperone 1
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000018085
InnateDB Gene IDBG-639136 (PSMG1)
Protein Structure
UniProt Annotation
Function Chaperone protein which promotes assembly of the 20S proteasome as part of a heterodimer with PSMG2. The PSMG1-PSMG2 heterodimer binds to the PSMA5 and PSMA7 proteasome subunits, promotes assembly of the proteasome alpha subunits into the heteroheptameric alpha ring and prevents alpha ring dimerization (By similarity). {ECO:0000250UniProtKB:O95456}.
Subcellular Localization Cytoplasm {ECO:0000250UniProtKB:O95456}. Endoplasmic reticulum {ECO:0000250UniProtKB:O95456}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.
Predicted by orthology
Total 6 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0070628 proteasome binding
Biological Process
GO:0021930 cerebellar granule cell precursor proliferation
GO:0043248 proteasome assembly
GO:0080129 proteasome core complex assembly
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005783 endoplasmic reticulum
Protein Structure and Domains
PDB ID
InterPro IPR016565 Proteasome assembly chaperone 1
PFAM
PRINTS
PIRSF PIRSF010076
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q0P5F2
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 614817
UniGene Bt.58975
RefSeq NP_001069815
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC120126
GenPept AAI20127

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca