Version 5.4
Bos taurus Protein: TMEM59
Summary
InnateDB Protein IDBP-691293.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TMEM59
Protein Name transmembrane protein 59 precursor
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000012534
InnateDB Gene IDBG-639159 (TMEM59)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004175 endopeptidase activity
GO:0004867 serine-type endopeptidase inhibitor activity
GO:0005515 protein binding
Biological Process
GO:0006508 proteolysis
GO:0006914 autophagy
GO:0010508 positive regulation of autophagy
GO:0010955 negative regulation of protein processing
GO:0090005 negative regulation of establishment of protein localization to plasma membrane
GO:0090285 negative regulation of protein glycosylation in Golgi
Cellular Component
GO:0000137 Golgi cis cisterna
GO:0000138 Golgi trans cisterna
GO:0000139 Golgi membrane
GO:0005764 lysosome
GO:0005765 lysosomal membrane
GO:0005768 endosome
GO:0005770 late endosome
GO:0005794 Golgi apparatus
GO:0005797 Golgi medial cisterna
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0031902 late endosome membrane
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID
InterPro IPR002223 Proteinase inhibitor I2, Kunitz metazoa
IPR022065 Uncharacterised protein family, TMEM59
PFAM PF00014
PF12280
PRINTS PR00759
PIRSF
SMART SM00131
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q3T0Q2
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 509775
UniGene
RefSeq NP_001030248
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC102302 DAAA02008837
GenPept AAI02303

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca