Version 5.4
Bos taurus Protein: VSX1
Summary
InnateDB Protein IDBP-691330.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol VSX1
Protein Name Visual system homeobox 1
Synonyms RINX;
Species Bos taurus
Ensembl Protein ENSBTAP00000004329
InnateDB Gene IDBG-639196 (VSX1)
Protein Structure
UniProt Annotation
Function Binds to the 37-bp core of the locus control region (LCR) of the red/green visual pigment gene cluster. May regulate the activity of the LCR and the cone opsin genes at earlier stages of development.
Subcellular Localization Nucleus {ECO:0000255PROSITE- ProRule:PRU00108}.
Disease Associations
Tissue Specificity Expressed in a subset of cells in the inner nuclear layer of the retina.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0043565 sequence-specific DNA binding
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0007275 multicellular organismal development
GO:0007601 visual perception
GO:0042551 neuron maturation
GO:0048666 neuron development
GO:0050896 response to stimulus
GO:0060040 retinal bipolar neuron differentiation
Cellular Component
GO:0005634 nucleus
Protein Structure and Domains
PDB ID
InterPro IPR001356 Homeobox domain
IPR009057 Homeodomain-like
PFAM PF00046
PRINTS
PIRSF
SMART SM00389
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9GMA3
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 286802
UniGene Bt.5555
RefSeq NP_777192
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL AF251032
GenPept AAF99655

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca