InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: MAP3K2

Summary

InnateDB Protein

IDBP-691373.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

MAP3K2

Protein Name

mitogen-activated protein kinase kinase kinase 2

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000005525

InnateDB Gene

IDBG-639222 (MAP3K2)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 25 interaction(s) predicted by orthology.

Predicted by orthology
Total	25 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000166	nucleotide binding
GO:0004672	protein kinase activity
GO:0004713	protein tyrosine kinase activity
GO:0005515	protein binding
GO:0005524	ATP binding
GO:0016772	transferase activity, transferring phosphorus-containing groups
GO:0019901	protein kinase binding

Biological Process

GO:0006468	protein phosphorylation
GO:0045893	positive regulation of transcription, DNA-templated
GO:0071260	cellular response to mechanical stimulus

Cellular Component

GO:0005634	nucleus
GO:0005737	cytoplasm

Protein Structure and Domains

PDB ID

InterPro

IPR000270 Phox/Bem1p
IPR000719 Protein kinase domain
IPR001245 Serine-threonine/tyrosine-protein kinase catalytic domain
IPR002290 Serine/threonine/dual specificity protein kinase, catalytic domain
IPR011009 Protein kinase-like domain
IPR020635 Tyrosine-protein kinase, catalytic domain

PFAM

PF00564
PF00069
PF07714

PRINTS

PR00109

PIRSF

SMART

SM00666
SM00220
SM00219

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

F1MSX4

UniProt Splice Variant

Entrez Gene

UniGene

Bt.92459

RefSeq

HUGO

HGNC:6854

OMIM

CCDS

HPRD

IMGT

EMBL

DAAA02003889

GenPept