Version 5.4
Bos taurus Protein: INA
Summary
InnateDB Protein IDBP-691432.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol INA
Protein Name Alpha-internexin
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000003517
InnateDB Gene IDBG-639291 (INA)
Protein Structure
UniProt Annotation
Function Class-IV neuronal intermediate filament that is able to self-assemble. It is involved in the morphogenesis of neurons. It may form an independent structural network without the involvement of other neurofilaments or it may cooperate with NF-L to form the filamentous backbone to which NF-M and NF-H attach to form the cross-bridges (By similarity). {ECO:0000250}.
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 10 interaction(s) predicted by orthology.
Predicted by orthology
Total 10 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005198 structural molecule activity
GO:0005515 protein binding
Biological Process
GO:0007275 multicellular organismal development
GO:0007399 nervous system development
GO:0021762 substantia nigra development
GO:0030154 cell differentiation
GO:0045104 intermediate filament cytoskeleton organization
GO:0060052 neurofilament cytoskeleton organization
Cellular Component
GO:0005615 extracellular space
GO:0005882 intermediate filament
GO:0005883 neurofilament
GO:0036464 cytoplasmic ribonucleoprotein granule
Protein Structure and Domains
PDB ID
InterPro IPR001664 Intermediate filament protein
IPR006821 Intermediate filament head, DNA-binding domain
IPR009053 Prefoldin
PFAM PF00038
PF04732
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q08DH7
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 532236
UniGene Bt.65345
RefSeq NP_001069426
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC123743
GenPept AAI23744

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca