InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: BT.48853

Summary

InnateDB Protein

IDBP-691434.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

BT.48853

Protein Name

major vault protein

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000010451

InnateDB Gene

IDBG-639287 (BT.48853)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 19 interaction(s) predicted by orthology.

Predicted by orthology
Total	19 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0019901	protein kinase binding
GO:0019903	protein phosphatase binding

Biological Process

GO:0008283	cell proliferation
GO:0023057	negative regulation of signaling
GO:0031953	negative regulation of protein autophosphorylation
GO:0038127	ERBB signaling pathway
GO:0061099	negative regulation of protein tyrosine kinase activity
GO:0072376	protein activation cascade

Cellular Component

GO:0005634	nucleus
GO:0005737	cytoplasm
GO:0005856	cytoskeleton
GO:0016020	membrane
GO:0048471	perinuclear region of cytoplasm
GO:0070062	extracellular vesicular exosome

Protein Structure and Domains

PDB ID

InterPro

IPR002499 Major vault protein, N-terminal
IPR021870 Shoulder domain

PFAM

PF01505
PF11978

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

F1MNN6

UniProt Splice Variant

Entrez Gene

516456

UniGene

Bt.48853

RefSeq

NP_001030394

HUGO

OMIM

CCDS

HPRD

IMGT

EMBL

DAAA02057900

GenPept