InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: SEPT1

Summary

InnateDB Protein

IDBP-691501.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

SEPT1

Protein Name

Septin-1

Synonyms

Septin-1;

Species

Bos taurus

Ensembl Protein

ENSBTAP00000028271

InnateDB Gene

IDBG-639351 (SEPT1)

Protein Structure

UniProt Annotation

Function

Filament-forming cytoskeletal GTPase (By similarity). May play a role in cytokinesis (Potential). {ECO:0000250, ECO:0000305}.

Subcellular Localization

Cytoplasm {ECO:0000250}. Cytoplasm, cytoskeleton {ECO:0000250}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000250}. Midbody {ECO:0000250}. Note=Remains at the centrosomes and the nearby microtubules throughout mitosis. Localizes to the midbody during cytokinesis (By similarity). {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.

Predicted by orthology
Total	5 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000166	nucleotide binding
GO:0003924	GTPase activity
GO:0005515	protein binding
GO:0005525	GTP binding

Biological Process

GO:0007049	cell cycle
GO:0051301	cell division

Cellular Component

GO:0005737	cytoplasm
GO:0005815	microtubule organizing center
GO:0005856	cytoskeleton
GO:0030496	midbody
GO:0031105	septin complex

Protein Structure and Domains

PDB ID

InterPro

IPR000038 Cell division protein GTP binding
IPR004881 Ribosome biogenesis GTPase RsgA, putative
IPR016491 Septin
IPR027417 P-loop containing nucleoside triphosphate hydrolase

PFAM

PF00735
PF03193

PRINTS

PIRSF

PIRSF006698

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

A5PJU9