Version 5.4
Bos taurus Protein: GLE1
Summary
InnateDB Protein IDBP-691610.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol GLE1
Protein Name Nucleoporin GLE1
Synonyms GLE1L;
Species Bos taurus
Ensembl Protein ENSBTAP00000020333
InnateDB Gene IDBG-639450 (GLE1)
Protein Structure
UniProt Annotation
Function Required for the export of mRNAs containing poly(A) tails from the nucleus into the cytoplasm. May be involved in the terminal step of the mRNA transport through the nuclear pore complex (NPC) (By similarity). {ECO:0000250}.
Subcellular Localization Nucleus {ECO:0000250}. Cytoplasm {ECO:0000250}. Nucleus, nuclear pore complex {ECO:0000250}. Note=Shuttles between the nucleus and the cytoplasm. Localizes to the nuclear pore complex and nuclear envelope. Shuttling is essential for its mRNA export function (By similarity). {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0042802 identical protein binding
Biological Process
GO:0006810 transport
GO:0015031 protein transport
GO:0016973 poly(A)+ mRNA export from nucleus
GO:0051028 mRNA transport
Cellular Component
GO:0005615 extracellular space
GO:0005634 nucleus
GO:0005643 nuclear pore
GO:0005737 cytoplasm
GO:0005886 plasma membrane
GO:0016020 membrane
Protein Structure and Domains
PDB ID
InterPro IPR012476 GLE1-like
PFAM PF07817
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q3ZBK7
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 540982
UniGene Bt.49512
RefSeq NP_001029890
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC103239
GenPept AAI03240

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca