InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: COX6A2

Summary

InnateDB Protein

IDBP-691803.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

COX6A2

Protein Name

Cytochrome c oxidase subunit 6A2, mitochondrial

Synonyms

COXVIAH;

Species

Bos taurus

Ensembl Protein

ENSBTAP00000026002

InnateDB Gene

IDBG-639627 (COX6A2)

Protein Structure

UniProt Annotation

Function

This protein is one of the nuclear-coded polypeptide chains of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport.

Subcellular Localization

Mitochondrion inner membrane.

Disease Associations

Tissue Specificity

Heart/muscle specific isoform.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.

Experimentally validated
Total	2 [view]
Protein-Protein	2 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	3 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004129	cytochrome-c oxidase activity

Biological Process

GO:1902600

hydrogen ion transmembrane transport

Cellular Component

GO:0005739	mitochondrion
GO:0005743	mitochondrial inner membrane
GO:0005751	mitochondrial respiratory chain complex IV
GO:0016020	membrane
GO:0016021	integral component of membrane
GO:0045277	respiratory chain complex IV

Protein Structure and Domains

PDB ID

InterPro

IPR001349 Cytochrome c oxidase, subunit VIa

PFAM

PF02046

PRINTS

PIRSF

PIRSF000277

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

P07471

PhosphoSite

PhosphoSite-

TrEMBL

UniProt Splice Variant

Entrez Gene

282200

UniGene

Bt.49093

RefSeq

NP_776947

HUGO

OMIM

CCDS

HPRD

IMGT

EMBL

BC103117 S64127 X56857

GenPept

AAB27605 AAI03118 CAA40183