Version 5.4
Bos taurus Protein: TRMT6
Summary
InnateDB Protein IDBP-692087.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TRMT6
Protein Name tRNA (adenine-N(1)-)-methyltransferase non-catalytic subunit TRM6
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000001734
InnateDB Gene IDBG-639889 (TRMT6)
Protein Structure
UniProt Annotation
Function Substrate-binding subunit of tRNA (adenine-N(1)-)- methyltransferase, which catalyzes the formation of N(1)- methyladenine at position 58 (m1A58) in initiator methionyl-tRNA. {ECO:0000250}.
Subcellular Localization Nucleus {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 8 interaction(s) predicted by orthology.
Predicted by orthology
Total 8 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003743 translation initiation factor activity
GO:0044822 poly(A) RNA binding
Biological Process
GO:0006413 translational initiation
GO:0006446 regulation of translational initiation
GO:0008033 tRNA processing
Cellular Component
GO:0005634 nucleus
Protein Structure and Domains
PDB ID
InterPro IPR007316 Eukaryotic initiation factor 3, gamma subunit
IPR017423 tRNA (adenine-N(1)-)-methyltransferase, non-catalytic TRM6 subunit
PFAM PF04189
PRINTS
PIRSF PIRSF038170
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q2T9V5
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 505816
UniGene Bt.5857
RefSeq NP_001033129
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC111249
GenPept AAI11250

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca