InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: EIF4H

Summary

InnateDB Protein

IDBP-692160.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

EIF4H

Protein Name

Eukaryotic translation initiation factor 4H

Synonyms

WBSCR1;

Species

Bos taurus

Ensembl Protein

ENSBTAP00000054254

InnateDB Gene

IDBG-639953 (EIF4H)

Protein Structure

UniProt Annotation

Function

Stimulates the RNA helicase activity of EIF4A in the translation initiation complex. Binds weakly mRNA (By similarity). {ECO:0000250}.

Subcellular Localization

Cytoplasm, perinuclear region {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 22 interaction(s) predicted by orthology.

Predicted by orthology
Total	22 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000166	nucleotide binding
GO:0003676	nucleic acid binding
GO:0003723	RNA binding
GO:0003743	translation initiation factor activity
GO:0005515	protein binding
GO:0044822	poly(A) RNA binding

Biological Process

GO:0006412	translation
GO:0006413	translational initiation
GO:0019953	sexual reproduction
GO:0048589	developmental growth

Cellular Component

GO:0005737	cytoplasm
GO:0016020	membrane
GO:0048471	perinuclear region of cytoplasm

Protein Structure and Domains

PDB ID

InterPro

IPR000504 RNA recognition motif domain

PFAM

PF00076

PRINTS

PIRSF

SMART

SM00360

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q1JPH6

PhosphoSite

PhosphoSite-

TrEMBL

A7MBG9

UniProt Splice Variant

Entrez Gene

517409

UniGene

Bt.99731

RefSeq

NP_001069220

HUGO

OMIM

CCDS

HPRD

IMGT

EMBL

BC151552 BT025377 BT030478 DAAA02058194

GenPept

AAI51553 ABF57333 ABQ12918