Version 5.4
Bos taurus Protein: TSPAN1
Summary
InnateDB Protein IDBP-692213.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TSPAN1
Protein Name Tetraspanin-1
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000017715
InnateDB Gene IDBG-640010 (TSPAN1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization Lysosome membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0015403 thiamine uptake transmembrane transporter activity
Biological Process
GO:0008283 cell proliferation
GO:0016477 cell migration
GO:0045807 positive regulation of endocytosis
GO:0050821 protein stabilization
GO:0071934 thiamine transmembrane transport
Cellular Component
GO:0005737 cytoplasm
GO:0005764 lysosome
GO:0005765 lysosomal membrane
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0031982 vesicle
GO:0048471 perinuclear region of cytoplasm
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID
InterPro IPR000301 Tetraspanin
IPR008952 Tetraspanin, EC2 domain
IPR018499 Tetraspanin/Peripherin
PFAM PF00335
PRINTS PR00259
PIRSF PIRSF002419
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q3T0S3
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 506550
UniGene Bt.13362
RefSeq NP_001029442
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC102280
GenPept AAI02281

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca