Version 5.4
Bos taurus Protein: CNP
Summary
InnateDB Protein IDBP-692309.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CNP
Protein Name 2',3'-cyclic-nucleotide 3'-phosphodiesterase
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000036278
InnateDB Gene IDBG-640095 (CNP)
Protein Structure
UniProt Annotation
Function May participate in RNA metabolism in the myelinating cell, CNP is the third most abundant protein in central nervous system myelin. {ECO:0000250}.
Subcellular Localization Membrane; Lipid-anchor. Melanosome {ECO:0000250}. Note=Firmly bound to membrane structures of brain white matter.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 10 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 10 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003723 RNA binding
GO:0003824 catalytic activity
GO:0004113 2',3'-cyclic-nucleotide 3'-phosphodiesterase activity
GO:0016787 hydrolase activity
Biological Process
GO:0007409 axonogenesis
GO:0008344 adult locomotory behavior
GO:0009214 cyclic nucleotide catabolic process
GO:0009636 response to toxic substance
GO:0021762 substantia nigra development
GO:0048709 oligodendrocyte differentiation
Cellular Component
GO:0005615 extracellular space
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005874 microtubule
GO:0016020 membrane
GO:0042470 melanosome
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID
InterPro IPR008431 Cyclic nucleotide phosphodiesterase
PFAM PF05881
PRINTS
PIRSF PIRSF000970
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P06623
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 280752
UniGene Bt.5517
RefSeq NP_851336
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC102820 J02659 M27606 Y00405
GenPept AAA30456 AAA30457 AAI02821 CAA68466

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca