InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: TSC1

Summary

InnateDB Protein

IDBP-692506.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

TSC1

Protein Name

hamartin

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000006842

InnateDB Gene

IDBG-640246 (TSC1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 59 interaction(s) predicted by orthology.

Predicted by orthology
Total	59 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005488	binding
GO:0005515	protein binding
GO:0030695	GTPase regulator activity
GO:0047485	protein N-terminus binding
GO:0051087	chaperone binding

Biological Process

GO:0001822	kidney development
GO:0001843	neural tube closure
GO:0001952	regulation of cell-matrix adhesion
GO:0006407	rRNA export from nucleus
GO:0006417	regulation of translation
GO:0006813	potassium ion transport
GO:0007160	cell-matrix adhesion
GO:0007399	nervous system development
GO:0008285	negative regulation of cell proliferation
GO:0017148	negative regulation of translation
GO:0021766	hippocampus development
GO:0021987	cerebral cortex development
GO:0030030	cell projection organization
GO:0032007	negative regulation of TOR signaling
GO:0032318	regulation of Ras GTPase activity
GO:0032862	activation of Rho GTPase activity
GO:0032868	response to insulin
GO:0032956	regulation of actin cytoskeleton organization
GO:0042552	myelination
GO:0043666	regulation of phosphoprotein phosphatase activity
GO:0045792	negative regulation of cell size
GO:0045859	regulation of protein kinase activity
GO:0046627	negative regulation of insulin receptor signaling pathway
GO:0050808	synapse organization
GO:0050821	protein stabilization
GO:0051492	regulation of stress fiber assembly
GO:0051726	regulation of cell cycle
GO:0051894	positive regulation of focal adhesion assembly
GO:0055007	cardiac muscle cell differentiation

Cellular Component

GO:0005737	cytoplasm
GO:0005829	cytosol
GO:0005884	actin filament
GO:0005938	cell cortex
GO:0016020	membrane
GO:0030027	lamellipodium
GO:0033596	TSC1-TSC2 complex
GO:0043234	protein complex