InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: BT.17324

Summary

InnateDB Protein

IDBP-692571.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

BT.17324

Protein Name

nuclear factor erythroid 2-related factor 2

Synonyms

NRF2;

Species

Bos taurus

Ensembl Protein

ENSBTAP00000025637

InnateDB Gene

IDBG-640320 (BT.17324)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 58 interaction(s) predicted by orthology.

Predicted by orthology
Total	58 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000980	RNA polymerase II distal enhancer sequence-specific DNA binding
GO:0001102	RNA polymerase II activating transcription factor binding
GO:0001205	RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0003677	DNA binding
GO:0003700	sequence-specific DNA binding transcription factor activity
GO:0005515	protein binding
GO:0019904	protein domain specific binding
GO:0043565	sequence-specific DNA binding

Biological Process

GO:0006355	regulation of transcription, DNA-templated
GO:0010499	proteasomal ubiquitin-independent protein catabolic process
GO:0016567	protein ubiquitination
GO:0030194	positive regulation of blood coagulation
GO:0030968	endoplasmic reticulum unfolded protein response
GO:0034599	cellular response to oxidative stress
GO:0036003	positive regulation of transcription from RNA polymerase II promoter in response to stress
GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0045893	positive regulation of transcription, DNA-templated
GO:0045944	positive regulation of transcription from RNA polymerase II promoter
GO:0045995	regulation of embryonic development
GO:0070301	cellular response to hydrogen peroxide
GO:0071356	cellular response to tumor necrosis factor
GO:0071499	cellular response to laminar fluid shear stress
GO:1902176	negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway
GO:2000121	regulation of removal of superoxide radicals
GO:2000352	negative regulation of endothelial cell apoptotic process
GO:2000379	positive regulation of reactive oxygen species metabolic process