Version 5.4
Bos taurus Protein: NUCB1
Summary
InnateDB Protein IDBP-692586.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol NUCB1
Protein Name Nucleobindin-1
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000003073
InnateDB Gene IDBG-640331 (NUCB1)
Protein Structure
UniProt Annotation
Function Major calcium-binding protein of the Golgi. May have a role in calcium homeostasis (By similarity). {ECO:0000250}.
Subcellular Localization Golgi apparatus, cis-Golgi network membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Lumenal side {ECO:0000250}. Cytoplasm {ECO:0000250}. Note=A small fraction of the protein may be cytoplasmic. {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 16 interaction(s) predicted by orthology.
Predicted by orthology
Total 16 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0005509 calcium ion binding
GO:0005515 protein binding
GO:0046872 metal ion binding
Biological Process
Cellular Component
GO:0005615 extracellular space
GO:0005737 cytoplasm
GO:0005793 endoplasmic reticulum-Golgi intermediate compartment
GO:0005794 Golgi apparatus
GO:0016020 membrane
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID
InterPro IPR002048 EF-hand domain
PFAM PF00036
PF13202
PF13405
PRINTS
PIRSF
SMART SM00054
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q0P569
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 505351
UniGene Bt.7930
RefSeq NP_001068667
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC120433
GenPept AAI20434

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca