InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: ATP6V0B

Summary

InnateDB Protein

IDBP-692594.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

ATP6V0B

Protein Name

V-type proton ATPase 21 kDa proteolipid subunit

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000025144

InnateDB Gene

IDBG-640337 (ATP6V0B)

Protein Structure

UniProt Annotation

Function

Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells (By similarity). {ECO:0000250}.

Subcellular Localization

Vacuole membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.

Predicted by orthology
Total	4 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0015078	hydrogen ion transmembrane transporter activity

Biological Process

GO:0006810	transport
GO:0006811	ion transport
GO:0015991	ATP hydrolysis coupled proton transport
GO:0015992	proton transport

Cellular Component

GO:0005768	endosome
GO:0005773	vacuole
GO:0005774	vacuolar membrane
GO:0016020	membrane
GO:0016021	integral component of membrane
GO:0033177	proton-transporting two-sector ATPase complex, proton-transporting domain
GO:0033179	proton-transporting V-type ATPase, V0 domain