InnateDB Protein
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IDBP-692692.2
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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FBXO25
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Protein Name
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F-box only protein 25
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Synonyms
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Species
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Bos taurus
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Ensembl Protein
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ENSBTAP00000009259
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InnateDB Gene
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IDBG-640428 (FBXO25)
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Protein Structure
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Function |
Substrate-recognition component of the SCF (SKP1-CUL1-F- box protein)-type E3 ubiquitin ligase complex. May play a role in accumulation of expanded polyglutamine (polyQ) protein huntingtin (HTT) (By similarity). {ECO:0000250}.
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Subcellular Localization |
Nucleus {ECO:0000250}. Note=In the nucleus, associates with subnuclear dot-like structure. {ECO:0000250}.
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 100 interaction(s) predicted by orthology.
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Predicted by orthology |
Total |
100 [view]
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
IPR001810
F-box domain
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PFAM |
PF00646
PF12937
PF13013
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PRINTS |
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PIRSF |
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SMART |
SM00256
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TIGRFAMs |
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Modification |
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SwissProt |
Q1RMS8
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PhosphoSite |
PhosphoSite-
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
540328
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UniGene |
Bt.1450
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RefSeq |
NP_001069679
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HUGO |
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OMIM |
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CCDS |
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HPRD |
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IMGT |
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EMBL |
BC114733
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GenPept |
AAI14734
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