InnateDB Protein
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IDBP-692818.2
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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CDCA7
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Protein Name
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Cell division cycle-associated protein 7
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Synonyms
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Species
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Bos taurus
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Ensembl Protein
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ENSBTAP00000004495
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InnateDB Gene
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IDBG-640546 (CDCA7)
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Protein Structure
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Function |
Participates in MYC-mediated cell transformation and apoptosis; induces anchorage-independent growth and clonogenicity in lymphoblastoid cells. Insufficient to induce tumorigenicity when overexpressed but contributes to MYC-mediated tumorigenesis. May play a role as transcriptional regulator (By similarity). {ECO:0000250}.
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Subcellular Localization |
Nucleus {ECO:0000250}. Cytoplasm {ECO:0000250}. Note=Predominantly nuclear with some expression also seen in the cytoplasm. Predominantly cytoplasmic when phosphorylated at Thr-163 (By similarity). {ECO:0000250}.
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
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Predicted by orthology |
Total |
2 [view]
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
IPR018866
Zinc-finger domain of monoamine-oxidase A repressor R1
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PFAM |
PF10497
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
Q32PH1
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PhosphoSite |
PhosphoSite-
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
614893
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UniGene |
Bt.42032
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RefSeq |
NP_001032565
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HUGO |
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OMIM |
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CCDS |
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HPRD |
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IMGT |
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EMBL |
BC108118
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GenPept |
AAI08119
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