Bos taurus Protein: CDCA7
Summary
InnateDB Protein IDBP-692818.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CDCA7
Protein Name Cell division cycle-associated protein 7
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000004495
InnateDB Gene IDBG-640546 (CDCA7)
Protein Structure
UniProt Annotation
Function Participates in MYC-mediated cell transformation and apoptosis; induces anchorage-independent growth and clonogenicity in lymphoblastoid cells. Insufficient to induce tumorigenicity when overexpressed but contributes to MYC-mediated tumorigenesis. May play a role as transcriptional regulator (By similarity). {ECO:0000250}.
Subcellular Localization Nucleus {ECO:0000250}. Cytoplasm {ECO:0000250}. Note=Predominantly nuclear with some expression also seen in the cytoplasm. Predominantly cytoplasmic when phosphorylated at Thr-163 (By similarity). {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0006915 apoptotic process
GO:0042127 regulation of cell proliferation
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
Protein Structure and Domains
PDB ID
InterPro IPR018866 Zinc-finger domain of monoamine-oxidase A repressor R1
PFAM PF10497
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q32PH1
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 614893
UniGene Bt.42032
RefSeq NP_001032565
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC108118
GenPept AAI08119