InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: DYRK1A

Summary

InnateDB Protein

IDBP-692842.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

DYRK1A

Protein Name

dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000002319

InnateDB Gene

IDBG-640554 (DYRK1A)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 34 interaction(s) predicted by orthology.

Predicted by orthology
Total	34 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000166	nucleotide binding
GO:0004672	protein kinase activity
GO:0004674	protein serine/threonine kinase activity
GO:0004712	protein serine/threonine/tyrosine kinase activity
GO:0004713	protein tyrosine kinase activity
GO:0004715	non-membrane spanning protein tyrosine kinase activity
GO:0005515	protein binding
GO:0005524	ATP binding
GO:0016772	transferase activity, transferring phosphorus-containing groups
GO:0042802	identical protein binding
GO:0043621	protein self-association
GO:0048156	tau protein binding

Biological Process

GO:0006468	protein phosphorylation
GO:0007623	circadian rhythm
GO:0018105	peptidyl-serine phosphorylation
GO:0018107	peptidyl-threonine phosphorylation
GO:0043518	negative regulation of DNA damage response, signal transduction by p53 class mediator
GO:0046777	protein autophosphorylation
GO:0090312	positive regulation of protein deacetylation

Cellular Component

GO:0030529

ribonucleoprotein complex

Protein Structure and Domains

PDB ID

InterPro

IPR000719 Protein kinase domain
IPR001245 Serine-threonine/tyrosine-protein kinase catalytic domain
IPR002290 Serine/threonine/dual specificity protein kinase, catalytic domain
IPR011009 Protein kinase-like domain
IPR020635 Tyrosine-protein kinase, catalytic domain

PFAM

PF00069
PF07714

PRINTS

PR00109

PIRSF

SMART

SM00220
SM00219

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt