Version 5.4
Bos taurus Protein: SLC25A12
Summary
InnateDB Protein IDBP-692985.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SLC25A12
Protein Name calcium-binding mitochondrial carrier protein Aralar1
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000022292
InnateDB Gene IDBG-640691 (SLC25A12)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 11 interaction(s) predicted by orthology.
Predicted by orthology
Total 11 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005313 L-glutamate transmembrane transporter activity
GO:0005509 calcium ion binding
GO:0015183 L-aspartate transmembrane transporter activity
Biological Process
GO:0006810 transport
GO:0015810 aspartate transport
GO:0015813 L-glutamate transport
GO:0043490 malate-aspartate shuttle
GO:0051592 response to calcium ion
GO:0055085 transmembrane transport
Cellular Component
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID
InterPro IPR002048 EF-hand domain
IPR002067 Mitochondrial carrier protein
IPR018108 Mitochondrial substrate/solute carrier
IPR023395 Mitochondrial carrier domain
PFAM PF00036
PF13202
PF13405
PF00153
PRINTS PR00926
PIRSF
SMART SM00054
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL A6QNM9
UniProt Splice Variant
Entrez Gene 539494
UniGene Bt.69173
RefSeq NP_001094664
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC148908 DAAA02004232
GenPept AAI48909

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca