InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: ADAMTS13

Summary

InnateDB Protein

IDBP-693045.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

ADAMTS13

Protein Name

ADAM metallopeptidase with thrombospondin type 1 motif, 13

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000020085

InnateDB Gene

IDBG-640733 (ADAMTS13)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.

Predicted by orthology
Total	2 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004175	endopeptidase activity
GO:0004222	metalloendopeptidase activity
GO:0005515	protein binding
GO:0008237	metallopeptidase activity
GO:0008270	zinc ion binding

Biological Process

GO:0006508	proteolysis
GO:0043171	peptide catabolic process

Cellular Component

GO:0005578	proteinaceous extracellular matrix
GO:0005615	extracellular space

Protein Structure and Domains

PDB ID

InterPro

IPR000859 CUB domain
IPR000884 Thrombospondin, type 1 repeat
IPR001590 Peptidase M12B, ADAM/reprolysin
IPR006586 ADAM, cysteine-rich
IPR013273 Peptidase M12B, ADAM-TS

PFAM

PF00431
PF00090
PF01421
PF08516

PRINTS

PR01857

PIRSF

SMART

SM00042
SM00209
SM00608

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

F1MVP0

UniProt Splice Variant

Entrez Gene

UniGene

RefSeq

HUGO

HGNC:1366

OMIM

CCDS

HPRD

IMGT

EMBL

DAAA02032346 DAAA02032347 DAAA02032348

GenPept