InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: ARPC1B

Summary

InnateDB Protein

IDBP-693144.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

ARPC1B

Protein Name

Actin-related protein 2/3 complex subunit 1B

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000056302

InnateDB Gene

IDBG-640842 (ARPC1B)

Protein Structure

UniProt Annotation

Function

Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. {ECO:0000250}.

Subcellular Localization

Cytoplasm, cytoskeleton {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 20 interaction(s) predicted by orthology.

Experimentally validated
Total	2 [view]
Protein-Protein	2 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	20 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003779	actin binding
GO:0005515	protein binding

Biological Process

GO:0030833	regulation of actin filament polymerization
GO:0034314	Arp2/3 complex-mediated actin nucleation

Cellular Component

GO:0005737	cytoplasm
GO:0005829	cytosol
GO:0005856	cytoskeleton
GO:0005885	Arp2/3 protein complex
GO:0015629	actin cytoskeleton
GO:0070062	extracellular vesicular exosome