InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: CTBP2

Summary

InnateDB Protein

IDBP-693180.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

CTBP2

Protein Name

C-terminal-binding protein 2

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000004404

InnateDB Gene

IDBG-640871 (CTBP2)

Protein Structure

UniProt Annotation

Function

Corepressor targeting diverse transcription regulators. Functions in brown adipose tissue (BAT) differentiation (By similarity). Isoform 2 probably acts as a scaffold for specialized synapses. {ECO:0000250}.

Subcellular Localization

Nucleus {ECO:0000305}. Cell junction, synapse {ECO:0000250}.

Disease Associations

Tissue Specificity

Isoform 2 is specifically localized in synaptic ribbon (at protein level). {ECO:0000269PubMed:11163272}.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 63 interaction(s) predicted by orthology.

Predicted by orthology
Total	63 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0016491	oxidoreductase activity
GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
GO:0048037	cofactor binding
GO:0051287	NAD binding

Biological Process

GO:0006351	transcription, DNA-templated
GO:0006355	regulation of transcription, DNA-templated
GO:0008152	metabolic process
GO:0030154	cell differentiation
GO:0045892	negative regulation of transcription, DNA-templated
GO:0050872	white fat cell differentiation
GO:0055114	oxidation-reduction process