InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: LRP2

Summary

InnateDB Protein

IDBP-693303.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

LRP2

Protein Name

low density lipoprotein receptor-related protein 2

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000005988

InnateDB Gene

IDBG-640945 (LRP2)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 33 interaction(s) predicted by orthology.

Predicted by orthology
Total	33 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005509	calcium ion binding
GO:0005515	protein binding

Biological Process

GO:0006766	vitamin metabolic process
GO:0006898	receptor-mediated endocytosis
GO:0008283	cell proliferation
GO:0030900	forebrain development

Cellular Component

GO:0005765	lysosomal membrane
GO:0005768	endosome
GO:0005783	endoplasmic reticulum
GO:0005794	Golgi apparatus
GO:0005903	brush border
GO:0005905	coated pit
GO:0016020	membrane
GO:0016324	apical plasma membrane
GO:0030139	endocytic vesicle
GO:0031526	brush border membrane
GO:0043235	receptor complex
GO:0045177	apical part of cell
GO:0070062	extracellular vesicular exosome

Protein Structure and Domains

PDB ID

InterPro

IPR000033 LDLR class B repeat
IPR000742 Epidermal growth factor-like domain
IPR001881 EGF-like calcium-binding domain
IPR002172 Low-density lipoprotein (LDL) receptor class A repeat
IPR009030 Insulin-like growth factor binding protein, N-terminal

PFAM

PF00058
PF00008
PF07645
PF00057

PRINTS

PR00261

PIRSF

SMART

SM00135
SM00181
SM00179
SM00192

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt