InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: FAP

Summary

InnateDB Protein

IDBP-693568.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

FAP

Protein Name

seprase

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000010702

InnateDB Gene

IDBG-641224 (FAP)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.

Predicted by orthology
Total	3 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0002020	protease binding
GO:0004175	endopeptidase activity
GO:0004252	serine-type endopeptidase activity
GO:0005515	protein binding
GO:0008233	peptidase activity
GO:0008236	serine-type peptidase activity

Biological Process

GO:0006508	proteolysis
GO:0010716	negative regulation of extracellular matrix disassembly
GO:0043542	endothelial cell migration

Cellular Component

GO:0005615	extracellular space
GO:0016020	membrane
GO:0030027	lamellipodium
GO:0045177	apical part of cell
GO:0045178	basal part of cell

Protein Structure and Domains

PDB ID

InterPro

IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain
IPR002469 Peptidase S9B, dipeptidylpeptidase IV N-terminal
IPR029058 Alpha/Beta hydrolase fold

PFAM

PF00326
PF00930

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-