InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: KLK6

Summary

InnateDB Protein

IDBP-693595.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

KLK6

Protein Name

kallikrein-6

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000020121

InnateDB Gene

IDBG-641258 (KLK6)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 10 interaction(s) predicted by orthology.

Predicted by orthology
Total	10 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003824	catalytic activity
GO:0004252	serine-type endopeptidase activity
GO:0005515	protein binding
GO:0008233	peptidase activity
GO:0008236	serine-type peptidase activity
GO:0016787	hydrolase activity

Biological Process

GO:0006508	proteolysis
GO:0045745	positive regulation of G-protein coupled receptor protein signaling pathway
GO:0070997	neuron death

Cellular Component

GO:0005576	extracellular region
GO:0005615	extracellular space
GO:0005634	nucleus
GO:0005737	cytoplasm
GO:0015630	microtubule cytoskeleton
GO:0030141	secretory granule
GO:0031965	nuclear membrane
GO:0045171	intercellular bridge

Protein Structure and Domains

PDB ID

InterPro

IPR001254 Peptidase S1
IPR001314 Peptidase S1A, chymotrypsin-type
IPR009003 Trypsin-like cysteine/serine peptidase domain
IPR015420 Peptidase S1A, nudel

PFAM

PF00089
PF09342

PRINTS

PR00722

PIRSF

SMART

SM00020

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

A6QQ95

UniProt Splice Variant

Entrez Gene

532677

UniGene

Bt.41581

RefSeq

NP_001094610

HUGO

OMIM

CCDS

HPRD

IMGT

EMBL

BC149713 DAAA02047526

GenPept

AAI49714