InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: SPO11

Summary

InnateDB Protein

IDBP-693645.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

SPO11

Protein Name

SPO11 meiotic protein covalently bound to DSB homolog (S. cerevisiae)

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000053612

InnateDB Gene

IDBG-641299 (SPO11)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003677	DNA binding
GO:0003824	catalytic activity
GO:0005524	ATP binding

Biological Process

GO:0000737	DNA catabolic process, endonucleolytic
GO:0001541	ovarian follicle development
GO:0006259	DNA metabolic process
GO:0007129	synapsis
GO:0007131	reciprocal meiotic recombination
GO:0007141	male meiosis I
GO:0007286	spermatid development
GO:0034502	protein localization to chromosome

Cellular Component

GO:0000781	chromosome, telomeric region
GO:0005694	chromosome

Protein Structure and Domains

PDB ID

InterPro

IPR002815 Spo11/DNA topoisomerase VI subunit A
IPR004084 Meiosis-specific protein Spo11
IPR004085 DNA topoisomerase VI, subunit A
IPR013048 Meiotic recombination, Spo11
IPR013049 Spo11/DNA topoisomerase VI, subunit A, N-terminal

PFAM

PF03533
PF04406

PRINTS

PR01550
PR01552
PR01551

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite