Version 5.4
Bos taurus Protein: SNX8
Summary
InnateDB Protein IDBP-693679.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SNX8
Protein Name Sorting nexin-8
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000018213
InnateDB Gene IDBG-641324 (SNX8)
Protein Structure
UniProt Annotation
Function May be involved in several stages of intracellular trafficking. May play a role in intracellular protein transport from early endosomes to the trans-Golgi network (By similarity). {ECO:0000250}.
Subcellular Localization Early endosome membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Cytoplasmic side {ECO:0000250}. Note=Colocalizes with retromer components. {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 10 interaction(s) predicted by orthology.
Predicted by orthology
Total 10 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0008289 lipid binding
GO:0035091 phosphatidylinositol binding
GO:0042802 identical protein binding
Biological Process
GO:0006810 transport
GO:0006886 intracellular protein transport
GO:0015031 protein transport
GO:0034498 early endosome to Golgi transport
Cellular Component
GO:0005768 endosome
GO:0016020 membrane
GO:0030904 retromer complex
GO:0031901 early endosome membrane
Protein Structure and Domains
PDB ID
InterPro IPR001683 Phox homologous domain
PFAM PF00787
PRINTS
PIRSF
SMART SM00312
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q2KHV6
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 614344
UniGene Bt.28467
RefSeq NP_001039998
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC112867
GenPept AAI12868

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca