Version 5.4
| Bos taurus Protein: LIM2 | |||||
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| Summary | |||||
| InnateDB Protein | IDBP-693715.2 | ||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||
| Gene Symbol | LIM2 | ||||
| Protein Name | Lens fiber membrane intrinsic protein | ||||
| Synonyms | |||||
| Species | Bos taurus | ||||
| Ensembl Protein | ENSBTAP00000004191 | ||||
| InnateDB Gene | IDBG-641357 (LIM2) | ||||
| Protein Structure |
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| UniProt Annotation | |||||
| Function | Present in the thicker 16-17 nm junctions of mammalian lens fiber cells, where it may contribute to cell junctional organization. Acts as a receptor for calmodulin. May play an important role in both lens development and cataractogenesis. | ||||
| Subcellular Localization | Membrane; Multi-pass membrane protein. | ||||
| Disease Associations | |||||
| Tissue Specificity | Eye lens specific. | ||||
| Comments | |||||
| Interactions | |||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
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| Gene Ontology | |||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Protein Structure and Domains | |||||
| PDB ID | |||||
| InterPro |
IPR003935
Lens fibre membrane intrinsic protein IPR004031 PMP-22/EMP/MP20/Claudin superfamily IPR004032 PMP-22/EMP/MP20 |
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| PFAM |
PF00822
PF13903 |
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| PRINTS |
PR01457
PR01453 |
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| PIRSF | |||||
| SMART | |||||
| TIGRFAMs | |||||
| Post-translational Modifications | |||||
| Modification | |||||
| Cross-References | |||||
| SwissProt | P20274 | ||||
| PhosphoSite | PhosphoSite-P20274 | ||||
| TrEMBL | |||||
| UniProt Splice Variant | |||||
| Entrez Gene | 281282 | ||||
| UniGene | Bt.431 | ||||
| RefSeq | NP_776527 | ||||
| HUGO | |||||
| OMIM | |||||
| CCDS | |||||
| HPRD | |||||
| IMGT | |||||
| EMBL | L04188 | ||||
| GenPept | AAA30621 | ||||