Version 5.4
Bos taurus Protein: PPP2R1A
Summary
InnateDB Protein IDBP-693819.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PPP2R1A
Protein Name serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000026449
InnateDB Gene IDBG-641451 (PPP2R1A)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 175 interaction(s) predicted by orthology.
Predicted by orthology
Total 175 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003823 antigen binding
GO:0004722 protein serine/threonine phosphatase activity
GO:0005488 binding
GO:0005515 protein binding
GO:0046982 protein heterodimerization activity
Biological Process
GO:0007059 chromosome segregation
GO:0070262 peptidyl-serine dephosphorylation
GO:2001241 positive regulation of extrinsic apoptotic signaling pathway in absence of ligand
Cellular Component
GO:0000159 protein phosphatase type 2A complex
GO:0000775 chromosome, centromeric region
GO:0005829 cytosol
Protein Structure and Domains
PDB ID
InterPro IPR000357 HEAT
IPR016024 Armadillo-type fold
IPR021133 HEAT, type 2
PFAM PF02985
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL A5D973
UniProt Splice Variant
Entrez Gene 535321
UniGene Bt.15718
RefSeq NP_001032554
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BT030492 DAAA02047571
GenPept ABQ12932

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca