Version 5.4
Bos taurus Protein: CD302
Summary
InnateDB Protein IDBP-693826.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CD302
Protein Name CD302 antigen
Synonyms DCL-1;
Species Bos taurus
Ensembl Protein ENSBTAP00000050116
InnateDB Gene IDBG-641458 (CD302)
Protein Structure
UniProt Annotation
Function Potential multifunctional C-type lectin receptor that may play roles in endocytosis and phagocytosis as well as in cell adhesion and migration. {ECO:0000250UniProtKB:Q8IX05}.
Subcellular Localization Membrane {ECO:0000255}; Single-pass type I membrane protein {ECO:0000255}. Cell projection, filopodium {ECO:0000250UniProtKB:Q8IX05, ECO:0000255}. Cytoplasm, cell cortex {ECO:0000250UniProtKB:Q8IX05, ECO:0000255}. Cell projection, microvillus {ECO:0000250UniProtKB:Q8IX05, ECO:0000255}. Note=Colocalizes with F-actin in filopodia, cellular cortex and microvilli of the apical cell surface. {ECO:0000250UniProtKB:Q8IX05, ECO:0000255}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0030246 carbohydrate binding
Biological Process
GO:0006909 phagocytosis
Cellular Component
GO:0005737 cytoplasm
GO:0005902 microvillus
GO:0005938 cell cortex
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0030175 filopodium
GO:0042995 cell projection
Protein Structure and Domains
PDB ID
InterPro IPR001304 C-type lectin
IPR016187 C-type lectin fold
PFAM PF00059
PRINTS
PIRSF
SMART SM00034
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt A8WH74
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 100126272
UniGene Bt.81816
RefSeq NP_001103661
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL AAFC03027417 BC105308 BK006292
GenPept AAI05309 DAA06088

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca