InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: SOX10

Summary

InnateDB Protein

IDBP-693923.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

SOX10

Protein Name

SRY (sex determining region Y)-box 10

Synonyms

SOX9;

Species

Bos taurus

Ensembl Protein

ENSBTAP00000034563

InnateDB Gene

IDBG-641549 (SOX10)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 11 interaction(s) predicted by orthology.

Experimentally validated
Total	2 [view]
Protein-Protein	2 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	11 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000978	RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0000980	RNA polymerase II distal enhancer sequence-specific DNA binding
GO:0000981	sequence-specific DNA binding RNA polymerase II transcription factor activity
GO:0001190	RNA polymerase II transcription factor binding transcription factor activity involved in positive regulation of transcription
GO:0003677	DNA binding
GO:0003682	chromatin binding
GO:0003700	sequence-specific DNA binding transcription factor activity
GO:0003705	RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity
GO:0005515	protein binding
GO:0042802	identical protein binding
GO:0044212	transcription regulatory region DNA binding

Biological Process

GO:0001701	in utero embryonic development
GO:0001755	neural crest cell migration
GO:0002052	positive regulation of neuroblast proliferation
GO:0006366	transcription from RNA polymerase II promoter
GO:0007422	peripheral nervous system development
GO:0014015	positive regulation of gliogenesis
GO:0030154	cell differentiation
GO:0030318	melanocyte differentiation
GO:0043066	negative regulation of apoptotic process
GO:0045893	positive regulation of transcription, DNA-templated
GO:0045944	positive regulation of transcription from RNA polymerase II promoter
GO:0048469	cell maturation
GO:0048484	enteric nervous system development
GO:0048546	digestive tract morphogenesis
GO:0048589	developmental growth
GO:0048709	oligodendrocyte differentiation
GO:0090090	negative regulation of canonical Wnt signaling pathway