Version 5.4
Bos taurus Protein: PANX1
Summary
InnateDB Protein IDBP-693991.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PANX1
Protein Name Pannexin 1
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000015932
InnateDB Gene IDBG-641615 (PANX1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003779 actin binding
GO:0005102 receptor binding
GO:0005262 calcium channel activity
GO:0005515 protein binding
GO:0015267 channel activity
GO:0022840 leak channel activity
GO:0051015 actin filament binding
GO:0055077 gap junction hemi-channel activity
Biological Process
GO:0002931 response to ischemia
GO:0006812 cation transport
GO:0006816 calcium ion transport
GO:0033198 response to ATP
GO:0034214 protein hexamerization
GO:0050715 positive regulation of cytokine secretion
GO:0050717 positive regulation of interleukin-1 alpha secretion
GO:0050718 positive regulation of interleukin-1 beta secretion
GO:0055085 transmembrane transport
Cellular Component
GO:0005783 endoplasmic reticulum
GO:0005886 plasma membrane
GO:0005921 gap junction
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0032059 bleb
Protein Structure and Domains
PDB ID
InterPro IPR000990 Innexin
PFAM PF00876
PRINTS PR01262
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL D7R519
UniProt Splice Variant
Entrez Gene 528169
UniGene Bt.95001
RefSeq NP_001232854
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02062286 DAAA02062287 DAAA02062288 DAAA02062289 HM036582
GenPept ADH10263

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca