Version 5.4
Bos taurus Protein: TMEM59L
Summary
InnateDB Protein IDBP-694018.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TMEM59L
Protein Name Transmembrane protein 59-like
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000010124
InnateDB Gene IDBG-641635 (TMEM59L)
Protein Structure
UniProt Annotation
Function Modulates the O-glycosylation and complex N- glycosylation steps occurring during the Golgi maturation of APP. Inhibits APP transport to the cell surface and further shedding (By similarity). {ECO:0000250}.
Subcellular Localization Golgi apparatus membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
Cellular Component
GO:0000139 Golgi membrane
GO:0005794 Golgi apparatus
GO:0016020 membrane
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID
InterPro IPR022065 Uncharacterised protein family, TMEM59
PFAM PF12280
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q0VCT2
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 507157
UniGene Bt.48796
RefSeq NP_001068769
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC120018
GenPept AAI20019

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca