Version 5.4
Homo sapiens Protein: GPR173
Summary
InnateDB Protein IDBP-69407.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol GPR173
Protein Name G protein-coupled receptor 173
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000331600
InnateDB Gene IDBG-69405 (GPR173)
Protein Structure
UniProt Annotation
Function Orphan receptor.
Subcellular Localization Cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
Disease Associations
Tissue Specificity Expressed at high levels in brain and ovary. Lower levels in small intestine. In brain regions, detected in all regions tested. Highest levels in the cerebellum and cerebral cortex.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0004930 G-protein coupled receptor activity
GO:0004968 gonadotropin-releasing hormone receptor activity
Biological Process
GO:0007165 signal transduction
GO:0007186 G-protein coupled receptor signaling pathway
GO:0097211 cellular response to gonadotropin-releasing hormone
GO:2001223 negative regulation of neuron migration
Cellular Component
GO:0005886 plasma membrane
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID
InterPro IPR000276 G protein-coupled receptor, rhodopsin-like
IPR017452 GPCR, rhodopsin-like, 7TM
PFAM PF00001
PRINTS PR00237
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9NS66
PhosphoSite PhosphoSite-Q9NS66
TrEMBL J3KPD1
UniProt Splice Variant
Entrez Gene 54328
UniGene Hs.193011
RefSeq NP_061842
HUGO HGNC:18186
OMIM 300253
CCDS CCDS14349
HPRD 02220
IMGT
EMBL AB040801 BC009861 BX322635 CH471154
GenPept AAH09861 BAA96647 CAI42530 EAW93142

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca