Version 5.4
Bos taurus Protein: IL11
Summary
InnateDB Protein IDBP-694224.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol IL11
Protein Name interleukin 11
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000054291
InnateDB Gene IDBG-641820 (IL11)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.
Predicted by orthology
Total 6 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005125 cytokine activity
GO:0005142 interleukin-11 receptor binding
GO:0008083 growth factor activity
Biological Process
GO:0008284 positive regulation of cell proliferation
GO:0033138 positive regulation of peptidyl-serine phosphorylation
GO:0043410 positive regulation of MAPK cascade
GO:0045944 positive regulation of transcription from RNA polymerase II promoter
GO:0046888 negative regulation of hormone secretion
GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation
Cellular Component
GO:0005737 cytoplasm
Protein Structure and Domains
PDB ID
InterPro IPR009079 Four-helical cytokine-like, core
IPR020412 Interleukin-11, mammalian
IPR020438 Interleukin-11
PFAM PF07400
PRINTS PR01943
PR01927
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL G3MXM3
UniProt Splice Variant
Entrez Gene 100337295
UniGene
RefSeq XP_002695431
HUGO HGNC:5966
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02047746 DAAA02047747
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca