Bos taurus Protein: MKL1
Summary
InnateDB Protein IDBP-694236.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol MKL1
Protein Name megakaryoblastic leukemia (translocation) 1
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000003407
InnateDB Gene IDBG-641821 (MKL1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 12 interaction(s) predicted by orthology.
Predicted by orthology
Total 12 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000976 transcription regulatory region sequence-specific DNA binding
GO:0003676 nucleic acid binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0003713 transcription coactivator activity
GO:0003779 actin binding
GO:0003785 actin monomer binding
GO:0005515 protein binding
GO:0043522 leucine zipper domain binding
Biological Process
GO:0010735 positive regulation of transcription via serum response element binding
GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0045893 positive regulation of transcription, DNA-templated
GO:0045944 positive regulation of transcription from RNA polymerase II promoter
GO:0051145 smooth muscle cell differentiation
GO:2001234 negative regulation of apoptotic signaling pathway
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
Protein Structure and Domains
PDB ID
InterPro IPR003034 SAP domain
IPR004018 RPEL repeat
PFAM PF02037
PF02755
PRINTS
PIRSF
SMART SM00513
SM00707
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL E1BDD9
UniProt Splice Variant
Entrez Gene 509011
UniGene Bt.1662
RefSeq XP_002687986
HUGO HGNC:14334
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02014713 DAAA02014714
GenPept