InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: TYR

Summary

InnateDB Protein

IDBP-694258.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

TYR

Protein Name

tyrosinase precursor

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000015679

InnateDB Gene

IDBG-641856 (TYR)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 7 interaction(s) predicted by orthology.

Predicted by orthology
Total	7 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004503	monophenol monooxygenase activity
GO:0005507	copper ion binding
GO:0005515	protein binding
GO:0016491	oxidoreductase activity
GO:0042803	protein homodimerization activity
GO:0046872	metal ion binding
GO:0046982	protein heterodimerization activity

Biological Process

GO:0008152	metabolic process
GO:0008283	cell proliferation
GO:0042438	melanin biosynthetic process
GO:0043473	pigmentation
GO:0048538	thymus development
GO:0055114	oxidation-reduction process

Cellular Component

GO:0005737	cytoplasm
GO:0042470	melanosome
GO:0048471	perinuclear region of cytoplasm

Protein Structure and Domains

PDB ID

InterPro

IPR002227 Tyrosinase copper-binding domain
IPR008922 Uncharacterised domain, di-copper centre

PFAM

PF00264

PRINTS

PR00092

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

F2Y8W1

UniProt Splice Variant

Entrez Gene

280951

UniGene

Bt.9028

RefSeq

NP_851344

HUGO

OMIM

CCDS

HPRD

IMGT

EMBL

DAAA02062459 HQ826962 JQ513975 JQ513976

GenPept

ADZ53915 AFJ39265 AFJ39266