InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: SREBF2

Summary

InnateDB Protein

IDBP-694427.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

SREBF2

Protein Name

sterol regulatory element binding transcription factor 2

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000018956

InnateDB Gene

IDBG-641973 (SREBF2)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 54 interaction(s) predicted by orthology.

Predicted by orthology
Total	54 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000978	RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0003677	DNA binding
GO:0003700	sequence-specific DNA binding transcription factor activity
GO:0005515	protein binding
GO:0008022	protein C-terminus binding
GO:0044212	transcription regulatory region DNA binding
GO:0046983	protein dimerization activity
GO:0070888	E-box binding

Biological Process

GO:0000122	negative regulation of transcription from RNA polymerase II promoter
GO:0006355	regulation of transcription, DNA-templated
GO:0010886	positive regulation of cholesterol storage
GO:0045944	positive regulation of transcription from RNA polymerase II promoter
GO:0055098	response to low-density lipoprotein particle stimulus
GO:0072368	regulation of lipid transport by negative regulation of transcription from RNA polymerase II promoter
GO:0090370	negative regulation of cholesterol efflux
GO:2000188	regulation of cholesterol homeostasis