InnateDB Protein
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IDBP-694540.2
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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ARFGAP3
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Protein Name
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ADP-ribosylation factor GTPase-activating protein 3
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Synonyms
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Species
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Bos taurus
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Ensembl Protein
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ENSBTAP00000050747
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InnateDB Gene
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IDBG-642117 (ARFGAP3)
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Protein Structure
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Function |
GTPase-activating protein (GAP) for ADP ribosylation factor 1 (ARF1). Hydrolysis of ARF1-bound GTP may lead to dissociation of coatomer from Golgi-derived membranes to allow fusion with target membranes (By similarity). {ECO:0000250UniProtKB:Q9NP61}.
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Subcellular Localization |
Cytoplasm {ECO:0000250UniProtKB:Q9NP61}. Golgi apparatus membrane {ECO:0000250UniProtKB:Q9NP61}; Peripheral membrane protein {ECO:0000250UniProtKB:Q9NP61}; Cytoplasmic side {ECO:0000250UniProtKB:Q9NP61}. Note=Also found on peripheral punctate structures likely to be endoplasmic reticulum-Golgi intermediate compartment. {ECO:0000250UniProtKB:Q9NP61}.
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
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Predicted by orthology |
Total |
3 [view]
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
IPR001164
Arf GTPase activating protein
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PFAM |
PF01412
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PRINTS |
PR00405
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PIRSF |
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SMART |
SM00105
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TIGRFAMs |
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Modification |
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SwissProt |
Q17R07
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PhosphoSite |
PhosphoSite-
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
532778
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UniGene |
Bt.6257
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RefSeq |
NP_001069442
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HUGO |
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OMIM |
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CCDS |
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HPRD |
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IMGT |
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EMBL |
BC118087
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GenPept |
AAI18088
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