Version 5.4
Bos taurus Protein: PACSIN2
Summary
InnateDB Protein IDBP-694547.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PACSIN2
Protein Name protein kinase C and casein kinase substrate in neurons 2
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000025683
InnateDB Gene IDBG-642127 (PACSIN2)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 20 interaction(s) predicted by orthology.
Predicted by orthology
Total 20 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0008092 cytoskeletal protein binding
GO:0008289 lipid binding
GO:0016301 kinase activity
GO:0042802 identical protein binding
GO:0070300 phosphatidic acid binding
Biological Process
GO:0016310 phosphorylation
GO:0030036 actin cytoskeleton organization
GO:0036010 protein localization to endosome
GO:0045806 negative regulation of endocytosis
GO:0048858 cell projection morphogenesis
GO:0070836 caveola assembly
GO:0072584 caveolin-mediated endocytosis
GO:0097320 membrane tubulation
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005901 caveola
GO:0005911 cell-cell junction
GO:0019898 extrinsic component of membrane
GO:0043231 intracellular membrane-bounded organelle
GO:0055038 recycling endosome membrane
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID
InterPro IPR001060 FCH domain
IPR001452 SH3 domain
IPR011511 Variant SH3 domain
PFAM PF00611
PF00018
PF14604
PF07653
PRINTS PR00452
PIRSF
SMART SM00055
SM00326
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL Q1RMR9
UniProt Splice Variant
Entrez Gene 540107
UniGene Bt.5013
RefSeq NP_001039933
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC114745 DAAA02014847 DAAA02014848
GenPept AAI14746

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca