InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: UBXN4

Summary

InnateDB Protein

IDBP-694647.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

UBXN4

Protein Name

UBX domain-containing protein 4

Synonyms

UBXD2;

Species

Bos taurus

Ensembl Protein

ENSBTAP00000020184

InnateDB Gene

IDBG-642207 (UBXN4)

Protein Structure

UniProt Annotation

Function

Involved in endoplasmic reticulum-associated protein degradation (ERAD). {ECO:0000250}.

Subcellular Localization

Endoplasmic reticulum membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}. Nucleus envelope {ECO:0000250}. Note=Both the N- and the C-terminus face the cytosol. Also found in the nucleus envelope contiguous to the ER (By similarity). {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 7 interaction(s) predicted by orthology.

Predicted by orthology
Total	7 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding

Biological Process

GO:0006986

response to unfolded protein

Cellular Component

GO:0005634	nucleus
GO:0005635	nuclear envelope
GO:0005737	cytoplasm
GO:0005783	endoplasmic reticulum
GO:0005789	endoplasmic reticulum membrane
GO:0016020	membrane

Protein Structure and Domains

PDB ID

InterPro

IPR001012 UBX domain
IPR012336 Thioredoxin-like fold
IPR029071 Ubiquitin-related domain

PFAM

PF00789
PF13098
PF13192
PF13462
PF13905

PRINTS

PIRSF

SMART

SM00166

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q3ZBU9

PhosphoSite

PhosphoSite-

TrEMBL

UniProt Splice Variant

Entrez Gene

536181

UniGene

Bt.49319

RefSeq

NP_001030491

HUGO

OMIM

CCDS

HPRD

IMGT

EMBL

BC103096

GenPept

AAI03097