Version 5.4
Bos taurus Protein: SGCB
Summary
InnateDB Protein IDBP-694651.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SGCB
Protein Name Beta-sarcoglycan
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000052639
InnateDB Gene IDBG-642214 (SGCB)
Protein Structure
UniProt Annotation
Function Component of the sarcoglycan complex, a subcomplex of the dystrophin-glycoprotein complex which forms a link between the F-actin cytoskeleton and the extracellular matrix. {ECO:0000250}.
Subcellular Localization Cell membrane, sarcolemma {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}. Cytoplasm, cytoskeleton {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.
Predicted by orthology
Total 6 [view]
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0007517 muscle organ development
GO:0048747 muscle fiber development
GO:0055013 cardiac muscle cell development
GO:0097084 vascular smooth muscle cell development
Cellular Component
GO:0005737 cytoplasm
GO:0005856 cytoskeleton
GO:0005886 plasma membrane
GO:0016010 dystrophin-associated glycoprotein complex
GO:0016011 dystroglycan complex
GO:0016012 sarcoglycan complex
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0042383 sarcolemma
Protein Structure and Domains
PDB ID
InterPro IPR006875 Sarcoglycan complex subunit protein
PFAM PF04790
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt A6QP70
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 535372
UniGene Bt.66812
RefSeq NP_001095658
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC149178
GenPept AAI49179

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca