InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: EN1

Summary

InnateDB Protein

IDBP-694854.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

EN1

Protein Name

engrailed homeobox 1

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000038170

InnateDB Gene

IDBG-642403 (EN1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.

Predicted by orthology
Total	4 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003677	DNA binding
GO:0003700	sequence-specific DNA binding transcription factor activity
GO:0005515	protein binding
GO:0043565	sequence-specific DNA binding

Biological Process

GO:0006355	regulation of transcription, DNA-templated
GO:0007275	multicellular organismal development
GO:0009953	dorsal/ventral pattern formation
GO:0009954	proximal/distal pattern formation
GO:0010468	regulation of gene expression
GO:0030182	neuron differentiation
GO:0030326	embryonic limb morphogenesis
GO:0030901	midbrain development
GO:0030902	hindbrain development
GO:0030917	midbrain-hindbrain boundary development
GO:0035115	embryonic forelimb morphogenesis
GO:0035264	multicellular organism growth
GO:0043473	pigmentation
GO:0045944	positive regulation of transcription from RNA polymerase II promoter
GO:0048666	neuron development
GO:0060173	limb development

Cellular Component

GO:0005634

nucleus

Protein Structure and Domains

PDB ID

InterPro

IPR000104 Antifreeze protein, type I
IPR000747 Homeodomain engrailed
IPR001356 Homeobox domain
IPR009057 Homeodomain-like
IPR019549 Homeobox engrailed, C-terminal
IPR020467 Potassium channel, voltage dependent, Kv1.4
IPR020479 Homeodomain, metazoa

PFAM

PF00046
PF10525

PRINTS

PR00308
PR00026
PR01511
PR00024

PIRSF

SMART

SM00389

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt