InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: STEAP3

Summary

InnateDB Protein

IDBP-694895.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

STEAP3

Protein Name

STEAP family member 3, metalloreductase

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000009356

InnateDB Gene

IDBG-642441 (STEAP3)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.

Predicted by orthology
Total	4 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000293	ferric-chelate reductase activity
GO:0005515	protein binding
GO:0008823	cupric reductase activity
GO:0052851	ferric-chelate reductase (NADPH) activity

Biological Process

GO:0006826	iron ion transport
GO:0009306	protein secretion
GO:0015677	copper ion import
GO:0055114	oxidation-reduction process
GO:0097461	ferric iron import into cell
GO:1902167	positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
GO:1990182	exosomal secretion

Cellular Component

GO:0005768	endosome
GO:0005771	multivesicular body
GO:0005886	plasma membrane

Protein Structure and Domains

PDB ID

InterPro

IPR013130 Ferric reductase transmembrane component-like domain
IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal

PFAM

PF01794
PF03807

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

TrEMBL

UniProt Splice Variant

Entrez Gene

UniGene

RefSeq

HUGO

OMIM

CCDS

HPRD

IMGT

EMBL

DAAA02005183

GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1)

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca